AI creates anti-cancer molecules for proteins that previously could not be targeted pharmacologically by leveraging quantum ...

Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the ...

Because UHFR1 is implicated as an oncogene in numerous types of cancer, the results have implications for treating many cancers, say Baylin and Kong: "We are really excited about moving this ...

Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease.

Scientists from Flinders University in Australia have made a surprising discovery about a recently identified type of genetic material called circular RNAs. Their research suggests that these ...

Researchers at the Harvard Medical School discovered that the enzyme GUK1 promotes lung cancer growth by boosting the ...

Researchers at the University of California at San Francisco have identified an RNA-binding protein that increased the ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

More than 70% of the known oncogenes and proto-oncogenes in cancer code for tyrosine kinases. Blocking tyrosine kinase activity therefore represents a rational approach to cancer therapy.

Preclinical analysis and clinical validation to identify biomarkers for trifluridine/tipiracil (FTD/TPI) efficacy with or without bevacizumab in patients with metastatic colorectal cancer. This is an ...

The newly-discovered TIMP1-CD63 signaling mechanism causes Kirsten rat sarcoma viral oncogene homologue (KRAS)-mutated cells found in about 90 percent of pancreatic cancer patients to evade ...

UC San Diego researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease ...