In the hour, entitled “Double Helix,” we got flashbacks that filled in the blanks about why Rowan’s med-school romance with geneticist Lark (Ben Feldman) in San Francisco came to an end.

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In comparison to the rest of the league, San Francisco was one of 12 NFL franchises that Prisco deemed to have four or more of the league’s top 100 free agents. The 49ers joined the world champion ...

It was a Murphy's Law season for the San Francisco 49ers. Injuries ate a talented San Francisco team alive, and there was ...

San Francisco 49ers CEO Jed York, NFL Commissioner Roger Goodell, President and CEO of the Bay Area Host Committee Zaileen ...

San Francisco 49ers executives, who also run English football club Leeds, are using artificial intelligence to help assess ...

The San Francisco 49ers’ search to replace recently-fired defensive coordinator Nick Sorensen has been somewhat confusing. Sorenson was fired after just one season in that role. San Francisco ...

The San Francisco 49ers will be reportedly looking to trade Wide Receiver Deebo Samuel this offseason. San Francisco also granted Samuel and his agent permission to seek a trade. Samuel is coming ...

The San Francisco 49ers have some decisions to make this offseason. After turning over some of the coaching staff with the hopes of improving a season that saw the team sit at home for the playoffs.

The San Francisco 49ers are one of dozens of teams expected to show interest in star Cleveland Browns defensive end Myles Garrett this offseason. The reigning NFL Defensive Player of the Year ...