Mr. Vought, an architect of Project 2025 who served in the first Trump administration, will be at the center of President Trump’s plans to upend the federal bureaucracy.

WASHINGTON — The Senate voted along party lines Thursday to confirm Russell Vought as the next head of the Office of Management and Budget despite fierce pushback from Democrats. Although Democrats have been divided over various Trump nominees, they unified in opposition to Vought.

Senator Chuck Schumer called Vought the ‘most radical nominee, who has the most extreme agenda’ and now heads the ‘most important agency in Washington’